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AACR Roundup

Wednesday, November 16, 2011
• Mirna Therapeutics Inc., of Austin, Texas, presented preclinical data showing that mimics of five tumor suppressor miRNAs, including miR-34 and let-7, significantly inhibited the growth of liver tumors compared to controls. The five miRNA mimics were complexed with a lipid nanoparticle delivery formulation and were found to be neither toxic nor immunostimulatory. Additional preclinical work is ongoing.

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