Missing Cancer-Aging Link?
Anti-Aging Family Member Sirt2 Sex-Specific Tumor Suppressor
By Anette Breindl
Friday, October 21, 2011
Researchers from the National Institutes of Health have shown that Sirt2, a member of the anti-aging sirtuin family, functions as a tumor suppressor and that it does so for different tumor types for males and females. In mice, knocking out Sirt2 led to high rates of breast tumors in females, while about a quarter of male mice (but only one out of 26 female mice) lacing the gene developed liver cancer.
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