Orchid BioSciences Inc., of Princeton, N.J., appointed Jack Ball senior vice president and general manager of its Life Sciences Group, Michael Boyce-Jacino chief technology officer, Russell Granzow vice president of corporate business development and strategy, Michael Pettigrew executive director of marketing and sales and James Marcella executive director of manufacturing and SNP operations.

Panacea Pharmaceuticals Inc., of Rockville, Md., appointed Donald Zelm vice president of finance.

Repligen Corp., of Needham, Mass., appointed Patrice Rioux vice president of medical research.

SYN X Pharma Inc., of Toronto, appointed Eric Fonberg chief operating officer.

Trimeris Inc., of Durham, N.C., made Lynn Smiley senior vice president of clinical research.