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Boneheadedness Beneficial for Young and Old Minds

By Anette Breindl
Science Editor

Thursday, September 26, 2013

Scientists have discovered that the bone-derived hormone osteocalcin can cross both the placenta and the blood-brain barrier, and that it influences both prenatal brain development and adult brain function and behavior. The findings bring additional insight into just how much control bones, which were once considered little more than calcified tubes, exert over other organs. That control, Gerard Karsenty told BioWorld Today, is not too surprising in the bigger picture, because energetically speaking, the skeleton is “an extremely expensive invention of evolution.”

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