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Implications for PARP Inhibitors?

BRCA1, 2 Mutations Boost Survival In Ovarian Cancer

By Anette Breindl
Science Editor

Wednesday, January 25, 2012
BRCA1 and BRCA2 mutations are bad news to their carriers; the genes, which were the first cancer susceptibility genes to be identified, strongly raise the risk of developing breast and ovarian cancers – in some cases, up to fivefold.

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