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IT'S ALL RIGHT THERE

Cancer vaccine works, if you know where to look

By Anette Breindl
Science Editor

Friday, January 31, 2014
Scientists reported recently that a therapeutic vaccine for precancerous cervical lesions induced strong immune responses. But those immune responses were only apparent when the team analyzed the cervical tissue itself, not when they used the standard approach of looking for activated immune cells in the blood. Beyond the specific trial, the findings suggested that it might be useful to look for new ways to evaluate therapeutic vaccines. “When we do a vaccine trial, we measure immune response in the blood,” Connie Trimble told BioWorld Today. “But at least with the tools we have now, it’s better to look elsewhere. . . . There are immune cell populations that you can’t see in the blood.”

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