• Cornerstone Pharmaceuticals Inc., of Cranbury, N.J., started a Phase II trial with CPI-613, its lead altered energy metabolism-directed drug candidate. The pilot study, sponsored by the Comprehensive Cancer Center of Wake Forest Baptist Medical Center, will evaluate the overall response rate for CPI-613 in patients with myelodysplastic syndrome who have been unresponsive to previous therapies. Secondary endpoints include overall survival, progression-free survival, safety and transfusion frequency.
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