• Clovis Oncology Inc., of Boulder, Colo., reported interim findings from the Phase I dose-escalation portion of its ongoing Phase I/II study of CO-1686, an oral, targeted covalent inhibitor of mutant forms of the epidermal growth factor receptor (EGFR), for the treatment of non-small-cell lung cancer (NSCLC) in patients with initial activating EGFR mutations and the dominant resistance mutation T790M.