Nongenetic Data Yield Risk Genes
Complex Diseases Can Start in Mendelian Genes
By Anette Breindl
Friday, September 27, 2013
Figuring out the contribution of any gene to complex disorders is a murky fishing expedition, done in waters muddied by the interaction of the gene in question with other genes and environmental influences. As a result, identifying genetic contributions to complex disorders has been slow going even when very large groups have been sequenced. Recently, scientists at the University of Chicago described a new way to identify risk genes that did not, at least initially, rely on sequencing the genes in question, or any sequencing at all.
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