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Dual Peptide Could ‘Transform’ Diabetes Treatment

By Sharon Kingman
Staff Writer

Tuesday, November 5, 2013

A composite molecule that targets the two primary hormones that are released by the gut following meals can reduce weight and lower blood sugar in animal models, raising hopes of new and more effective treatments for obesity and diabetes. Clinical trials showed that the molecule was well tolerated and reduced blood glucose levels more than existing pharmacological treatments. Matthias Tschöp, professor of metabolic diseases at the Technische Universität München in Munich, Germany, said the results obtained by modulating the signaling of natural gut hormones suggested this approach has “potential for a transformative diabetes treatment.”

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