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Flip Side of Mental Retardation Protein Is Cancer Metastasis

By Sharon Kingman
Staff Writer

Tuesday, September 24, 2013
LONDON – A protein that has a role in causing the most frequent form of inherited mental retardation has turned out to be a master regulator of a large group of molecules involved in cancer progression and metastasis. While the absence of the Fragile X mental retardation protein (FMRP) causes inherited intellectual disability in individuals with Fragile X syndrome (FXS), the levels of that protein are often high in cancers, and encourage cancer cells to metastasize, a new international study has shown.

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