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Gene therapy scope broadens, again, with immune tolerance work

By Anette Breindl
Senior Science Editor

Thursday, September 21, 2017

By delivering the gene for myelin oligodendrocyte glycoprotein, one of the proteins that is a frequent target of autoimmune attack in multiple sclerosis, to the liver, researchers have been able to induce systemic immune tolerance. Depending on the timing of treatment, the approach could prevent or reverse the symptoms of even late-stage experimental autoimmune encephalitis, the mouse equivalent of MS.

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