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Tipplers vs. Teetotalers

Glutamate Receptor Separates Drinking and Nondrinking Rats

By Anette Breindl
Science Editor

Wednesday, October 2, 2013

By using modern sequencing methods to look at two strains of rats that either prefer or abhor alcohol, researchers have identified a glutamate receptor that has an early stop codon and so is for all intents and purposes missing in the drinkers.

The results, which the team published in the Sept 30, 2013, issue of the Proceedings of the National Academy of Sciences, are part of a larger body of work, by this team and others, indicating that glutamate transmission is different in alcoholics and those prone to the disease than in those who are not.

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