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SANS RIBAVIRIN, CIRRHOTICS TOO

HCV regimen wins in Phase III; Street’s ‘ION’ Gilead pricing

By Randy Osborne
Staff Writer

Thursday, December 19, 2013

Ribavirin (RBV) could drop out of hepatitis C virus (HCV) therapy for genotype 1 (GT1) patients, as a result of Gilead Sciences Inc.’s triumph in the Phase III program known as ION, which tested the once-daily, fixed-dose combination of its approved nucleotide analog polymerase inhibitor Sovaldi (sofosbuvir) and the NS5A inhibitor ledipasvir, with and without RBV.

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