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EFFICACY TRUMPS ALL?

Hyperglycemia eclipses promising PFS data for Clovis' CO-1686

By Jennifer Boggs
Managing Editor

Monday, June 2, 2014
Elevated glucose levels emerging in roughly one-fourth of lung cancer patients receiving Clovis Oncology Inc.'s next-generation EGFR inhibitor CO-1686 may have overshadowed the promising interim progression-free survival (PFS) rate presented at the American Society of Clinical Oncology meeting over the weekend, at least on Wall Street, but analysts say the targeted covalent inhibitor remains a contender against Astrazeneca plc's AZD9291.

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