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Good Enough Binding

Ignore Antigens for Antibody Biomarker Identification

By Anette Breindl

Friday, January 7, 2011
Disease-specific antibodies that could be isolated from blood serum would make great diagnostic markers. But to date, few such antibodies have been identified. Now, a research team suggests that this may be because researchers have been looking for binding in all the wrong places – and showed that by using synthetic peptoids, they were able to isolate diagnostic antibodies for both an animal model of multiple sclerosis, and for Alzheimer's disease.

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