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Induced Stem Cells Made Directly in Mice

By Anette Breindl
Science Editor

Wednesday, September 11, 2013
Since their initial description in 2007, induced pluripotent stem (iPS) cells have been investigated as a possible alternative to embryonic stem cells. By adding a cocktail of so-called reprogramming factors, scientists can turn mature cells – most often skin cells – into pluripotent cells that can turn into many different cell types. So far, iPS cells have been made in cell culture, with the goal of first making iPS cells from skin cells, differentiating them into the desired cell type, and using them for research or transplanting them back into patients.

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