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Putting Selfish Genes to Work

Jumping Gene Enzyme Used for Epigenomic Profiling

By Anette Breindl
Science Editor

Tuesday, October 8, 2013
Scientists have developed a method for rapidly profiling the epigenetic state of the entire genome, an advance which opens the door to new insights into which parts of a cell’s DNA are ready to be put to work at any given moment. They published their work in the Oct. 6, 2013, issue of Nature Methods. The method is not quite real time. But “you can do the whole epigenome in less than a day,” senior author Howard Chang told BioWorld Today. And much of the time it takes for an epigenomic profile is due to the time it takes to sequence the DNA, so increases in the speed of sequencing automatically increase the speed of epigenomic profiling as well.

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