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Things fall apart

Lack of epigenetic enzyme leaves neurons a TAD disorganized

By Anette Breindl
Senior Science Editor

Monday, July 3, 2017

Changes in the 3-D organization of chromosomes in neurons affected the expression of genes that are important for the formation of neuronal connections and that have been implicated in schizophrenia risk, researchers at the Mount Sinai School of Medicine reported in the July 3, 2017, issue of Nature Genetics.

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