Company (Location)

Company (Location)

Value (M)

Type/Product Area

Terms/Details (Date)


October

Affitech A/S (Copenhagen, Denmark)

GE Healthcare Life Sciences (Chalfont St. Giles, UK)

ND

Exclusive worldwide license for marketing and sales of products contaning recombinant Protein L

Affitech will receive a royalty on net product sales (10/18)

Alexza Pharmaceuticals Inc. (Mountain View, Calif.)

Gruppo Ferrer International SA (Barcelona, Spain)

$10

Deal for commercial rights in Europe, Latin America, Russia and the Common-wealth of Independent States countries for Adasuve for schizophrenia or bipolar disorder

Grupo will handle regulatory filings, and Alexza will receive milestone payments (10/7)

Ausio Pharmaceuticals LLC (Cincinnati)

Marshall Edwards Inc. (San Diego)

ND

Agreement giving Ausio exclusive, worldwide rights under certain Marshall Edwards patents to develop, manufacture and sell products using the isoflavone metabolite equol for applications outside oncology

Marshall Edwards is entitled to receive royalty payments on sales of Ausio products that contain equol; the deal also gives Marshall Edwards a royalty-free license to certain issued manufacturing-related intellectual property owned by Ausio (10/28)

Gilead Sciences Inc. (Foster City, Calif.)

Bristol-Myers Squibb Co. (New York)

ND

Liense agreement under which BMS will commercialize a fixed-dose HIV combination drug containing BMS' protease inhibitor Reyataz and Gilead's boosting agent cobicistat

BMS will be responsible for the formulation, manufacturing, development, registration, distribution and commercialization of the combination product, and Gilead will receive an undisclosed royalty (10/27)

Ligand Pharmaceuticals Inc. (La Jolla, Calif.)

Chiva Pharmaceuticals Inc. (Los Altos Hills, Calif.)

$4

Global licensing deal for Fablyn, approved in the European Union in 2009 to treat osteoporosis in postmenopausal women at increased risk of fracture

Ligand will receive $4M in licensing payments over the next eight months and is eligible for milestones and royalties on worldwide Fablyn sales (10/11)

Melmed Holdings AG (Switzerland)

Uluru Inc. (Addison, Texas)

ND

Binding letter of intent to license Altrazeal, a product for diabetic foot ulcers

Melmed will pay a licensing fee plus 25% interest in the Altrazeal marketing subsidiary; Uluru will supply Altrazeal at 30% of the European sales price and will receive royalties on sales within the European territory (10/14)

The Medicines Co. GmbH (Parsippany, N.J.)

Daiichi Sankyo Deutschland GmbH (Japan)

ND

Deal to co-promote Angiox in Germany, beginning Nov. 1

The Medicines Co.'s Angiox is indicated in Europe as an anticoagulant for adult patients undergoing percutaneous coronary intervention; financial terms were not disclosed (10/31)

November

Albany Molecular Research Inc. (Albany, N.Y.)

Eli Lilly and Co. (Indianapolis)

ND

Collaboration under which AMRI expects to hire more than 40 synthetic chemists by the third quarter of 2012 to support Lilly's drug discovery programs

The term of the collaboration is six years (11/9)

Ipsen SA (Paris)

Britannia Pharmaceuticals Ltd. (Redhill, UK)

ND

Ipsen sold North American rights for Apokyn, indicated in the U.S. for acute, intermittent treatment of hypomobility "off" episodes associated with Parkinson's disease

Ipsen had picked up rights to the drug in 2008 through its acquisition of Vernalis plc; Britannia agreed to pay more than one time the 2010 sales (11/3)

Phosphagenics Ltd. (Melbourne, Australia)

Themis Medicare Pvt Ltd. (Mumbai, India)

ND

Licensing agreement for TPM/diclofenac for the Indian market

Themis agreed to pay Phosphagenics an up-front fee and double-digit royalties on sales (11/3)


Notes:

The date indicated refers to the BioWorld Today issue in which the news item can be found.

** Denotes the date the item ran in BioWorld International.