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Mezzion’s PDE5 inhibitor enters U.S. trials for Fontan patients

By Shannon Ellis
Staff Writer

Wednesday, January 22, 2014

SHANGHAI – Mezzion Pharma Co. Ltd., of Seoul, South Korea, has signed an agreement with New England Research Institutes Inc. (NERI) to conduct government-sponsored clinical trials for udenafil. A long-acting phosphodiesterase type 5 (PDE5) inhibitor first approved in Korea and Russia for erectile dysfunction, udenafil will be trialed as a treatment for adolescents who face shortened lifespans due to reduced heart function due to congenital heart defects.

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