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Nanoparticle unsticks inflammatory cells

By Anette Breindl
Science Editor

Monday, February 24, 2014
Scientists have developed a nanoparticle that was able to specifically inhibit neutrophils – a type of white blood cell that plays important roles in infection and inflammation – from exiting out of blood vessels and into tissues to cause inflammatory damage. In animals with an experimentally induced version of sepsis, they found that treatment with the particles reduced injury to the lungs. The findings, Asrar Malik told BioWorld Today, were “based on our longstanding interest in albumin as a carrier molecule.” Albumin’s role in the body is to function as a delivery vehicle, getting hormones, lipids and other biological molecules to where they are needed.

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