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New TB vaccine could enter clinical trials within two years

By Sharon Kingman
Staff Writer

Monday, January 6, 2014

LONDON – A candidate vaccine to protect against tuberculosis can protect mice against the disease at least as well as the current vaccine in use, the live bacillus Calmette-Guérin (BCG). Importantly, the vaccine does not include two antigens that are used in current diagnostic tests, called ESAT-6 and CFP10, as this would make it impossible to tell whether someone was infected or had simply been vaccinated. Claus Aagaard, senior scientist at the Staten Serums Institute in Copenhagen, Denmark, told BioWorld Today, “We hope to start clinical trials within two years."

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