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Newly Identified Enzyme Could Rival PARPs as a Drug Target

By Sharon Kingman
Staff Writer

Tuesday, March 12, 2013
Study of a family affected by an inherited neurological disease has helped to reveal the identity of an enzyme that could point the way to new therapies for cancer and cardiovascular disease. The existence of the enzyme, which plays a role in maintaining cell survival and DNA repair, has been predicted for at least 30 years and has even been shown to operate in cell cultures.

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