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No pain, life span gain, scientists find

By Anette Breindl
Science Editor

Thursday, May 22, 2014
It has been known for some time now that a simple – but not an easy – way to live longer is to eat less. Caloric restriction extends the life span of organisms from worms to primates, suggesting that the method works, as well, for the rare human who is willing and able to stick to it. Now, researchers from the University of California at Berkeley finally have a better deal on offer – live longer through suffering less pain. Senior author Andrew Dillin and his colleagues found that they were able to expand the life span of mice by about four months, or 15 percent, by knocking out their TRPV-1 receptors, which sense pain, inflammation and heat. They published their findings in the May 22, 2014, issue of Cell.

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