• CellAct Pharma GmbH, of Dortmund, Germany, said its topoisomerase inhibitor CAP7.1 showed promising safety and tolerability in heavily pretreated solid tumors. The compound also demonstrated signs of efficacy in most treated patients, suggesting longer overall survival in lung, hypopharnyx, ovarian, testicular, stomach, esophageal, biliary tract and neuroendocrine tumors.