• Carolus Therapeutics Inc., of San Diego, and The Alpha-1 Project Inc. (TAP), a wholly owned subsidiary of the Alpha-1 Foundation, are collaborating to characterize human biological samples for the presence of the target, RANTES:PF4 heterodimer, a soluble protein complex that is secreted by activated platelets and implicated in many inflammation-related diseases, including genetic emphysema and chronic obstructive pulmonary disease.