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Can Have One Without the Other

P53 Tumor Suppression Works Without DNA Damage Repair

By Anette Breindl


Monday, May 23, 2011
P53 is a regulatory protein well known to cancer researchers and biotech firms alike. It is mutated in more than half of all human cancers. Even where it is not outright mutated, its functions appear compromised in most cancers. And some research has indicated that loss of p53 can turn cells into cancer stem cells. (See BioWorld Today, Sept. 21, 2009.)

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