Antares Pharma Inc., of Ewing, N.J., said it received a second milestone payment of $5 million from Leo Pharma A/S, of Ballerup, Denmark, in connection with the launch of psoriasis drug Otrexup (methotrexate) and the achievement of a specific percentage of patient lives covered by managed care organizations. To date, Antares has received $10 million in milestone payments from Leo.