Company
(symbol)#*

Date filed

Shares/units (M)

Price

Shares out@

Lead, other underwriters

Gross (US$M)

INITIAL OFFERINGS

Advanced Inhalation Therapies Ltd. (Tel Aviv, Israel; AITP)

8/27/15

N/A

N/A

N/A

N/A

$36

Altheadx Inc. (San Diego; IDGX)

12/23/14

N/A

N/A

17.9

Citigroup (co-lead); Jefferies (co-lead); William Blair; Cantor Fitzgerald

$69

Anaptysbio Inc. (San Diego; ANAB)

9/9/15

N/A

N/A

N/A

BMO Capital Markets (co-lead); Stifel Nicolaus & Co. (co-lead); JMP Securities; Wedbush Securities

$86.25

Anterios Inc. (New York; ANTE)

4/2/15

3.9S

$12-$14

N/A

Stifel (co-lead); RBC Capital Markets (co-lead); JMP Securities; Needham & Co.

$50.7

Audentes Therapeutics Inc. (BOLD)

1/4/16

N/A

N/A

N/A

BofA Merrill Lynch (co-lead); Cowen and Co. (co-lead); Wedbush Pacgrow

$86.25

Bavarian Nordic A/S (Copenhagen, Denmark; BAVA)1

1/5/16

ADS

N/A

N/A

Cowen and Co.; Piper Jaffray; Nomura Securities International (lead)

N/A

Biocardia Inc. (San Carlos, Calif.; BCDA)

6/16/15

N/A

N/A

N/A

Cantor Fitzgerald (co-lead); Roth Capital Partners (co-lead); Maxim Group

N/A

Cancer Prevention Pharmaceuticals Inc. (Tucson, Ariz.; NYSE:CPP)

12/24/15

N/A

N/A

N/A

Aegis Capital (lead)

$28.75

Clarus Therapeutics Inc. (Northbrook, Ill.; CLRS)

5/23/14

N/A

N/A

N/A

Citigroup (co-lead); Credit Suisse (co-lead); Canaccord Genuity; Needham & Co.

$86.25

Corvus Pharmaceuticals Inc. (Burlingame, Calif.; CRVS)

1/6/16

N/A

N/A

N/A

Credit Suisse, Cowen and Co.; Guggenheim Securities; Cantor Fitzgerald; BTIG

$115

Editas Medicine Inc. (Cambridge, Mass.; EDIT)

1/6/16

N/A

N/A

N/A

Morgan Stanley (co-lead); J.P. Morgan (co-lead); Cowen and Co.; JMP Securities

$100

Gelesis Inc. (Cambridge, Mass.; GLSS)

4/1/15

4S

$12-$14

N/A

Piper Jaffray (co-lead); Stifel (co-lead); Guggenheim Securities (co-lead)

$52

Gensight Biologics SA (Paris; GNST)2

7/7/15

4.65ADS

$13-$15

N/A

Leerink (co-lead); Evercore ISI (co-lead); Canaccord Genuity (co-lead)

$65

Lumena Pharmaceuticals Inc. (San Diego; LIVR)

4/2/14

N/A

N/A

N/A

Citigroup (co-lead); Cowen and Co. (co-lead); Leerink Partners (co-lead)

$75

Merus BV (Utrecht, the Netherlands; MRUS)

10/22/15

N/A

N/A

N/A

Citi; Jefferies

$60

Oncore Biopharma Inc. (Doylestown, Pa.)

11/25/14

N/A

N/A

N/A

N/A

N/A

Plx Pharma Inc. (Houston; PLXP)

10/8/15

N/A

N/A

5.56

Raymond James (co-lead); Maxim Group (co-lead); Janney Montgomery Scott

$80.5

Proteostasis Therapeutics Inc. (Cambridge, Mass.; PTI)

12/23/15

N/A

N/A

N/A

Leerink Partners (lead); RBC Capital Markets (lead); Baird;
H.C. Wainwright

$86.3

Reata Pharmaceuticals Inc. (Irving, Texas; RETA)3

1/6/16

N/A

N/A

N/A

Citigroup; Cowen and Co.; Piper Jaffray

$80

Revo Biologics Inc. (Framingham, Mass.; RBIO)4

6/25/14

3.6S

$13-$15

18.4

Piper Jaffray (co-lead); Guggenheim Securities (co-lead); Roth Capital Partners; BTIG

$50.4

Samsung Bioepsis (South Korea; joint venture of Samsung Biologics and Biogen Inc., of Cambridge, Mass.)

8/24/15

N/A

N/A

N/A

N/A

KRW1.5T (US$1.3B)

Sancilio Pharmaceuticals Inc. (Riviera Beach, Fla.; SPCI)

9/2/15

N/A

N/A

N/A

N/A

$86.25

Spring Bank Pharmaceuticals Inc. (Milford, Mass.; SBPH)

1/5/16

N/A

N/A

N/A

William Blair (co-lead); Wedbush Pacgrow (co-lead); BTIG

$57.5

Syndax Pharmaceuticals Inc. (Waltham, Mass.; SNDX)

1/6/16

N/A

N/A

N/A

Morgan Stanley (co-lead); Citigroup (co-lead)

$86.25

Therapure Biopharma Inc. (Mississauga, Ontario)

12/1/15

N/A

N/A

N/A

GMP Securities (co-lead); CIBC World Markets (co-lead); National Bank Financial (co-lead)

N/A

Tigenix NV (Leuven, Belgium; TIG; BR:TIG)5

12/24/15

ADS

N/A

N/A

Canaccord Genuity (co-lead); Nomura (co-lead); KBC Securities; Chardan Capital Markets

N/A

Visterra Inc. (Cambridge, Mass.; Cambridge, Mass.; VIST)

1/7/16

N/A

N/A

N/A

Leerink Partners (co-lead); Stifel (co-lead); Needham & Co.; Wedbush Pacgrow

$69

Viventia Bio Inc. (Winnipeg, Manitoba; VITA)

10/23/15

N/A

N/A

13

Leerink Partners; Cowen and Co.; Guggenheim Securities

$86.25

Yichang HEC Changjiang Pharmaceutical Co. Ltd. (China)6

12/16/15

N/A

N/A

N/A

N/A

HK$1.67B (US$215M)

Notes

# Unless otherwise indicated, shares are traded on the Nasdaq exchange.

* Stock symbols for companies seeking to complete IPOs are proposed.

@ This column reflects the shares outstanding following the offering, when disclosed.

N/A = Not available, applicable or reported.

The value of all offerings is based on either the midpoint of the price range listed in the company's SEC filing or the maximum aggregate offering price listed in the SEC filing.

This chart includes only biotech companies that develop therapeutics.

1 Bavarian Nordic filed Form F-1 for a proposed IPO of American depositary shares (ADS) to be listed on Nasdaq under the symbol BAVN.

2 Gensight's overallotment option: 697,500 ADSs.

3 Reata filed to raise up to $80M in an IPO of class A common shares.

4 Revo's overallotment option: 540,000 shares.

5 Tigenix filed a Form F-1 for a proposed IPO of its American depository shares to be listed on Nasdaq. The company's ordinary shares are currently listed on Euronext Brussels.

6 Yichang launched an IPO in Hong Kong.