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A ‘NEURODEGENERATAL’ DISORDER

Rare brain disorder results from faulty tRNA processing

By Anette Breindl
Science Editor

Friday, April 25, 2014
Researchers have identified a novel brain disorder that is neurodegenerative, but so early onset that it disrupts development, leading to disturbances in the formation and function of hindbrain structures. The specific mutation leading to the condition is rare. But they suggest that the split between neurodevelopmental disorders, where neurons or circuits fail to form correctly, and neurodegenerative disorders, where neurons or circuits are damaged after they are formed, is not an absolute one. “We tend to think of things as being degenerative or developmental,” Joseph Gleeson told BioWorld Today.

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