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Fabulous Fruit Fly + Smart Chemist = Cancer Drug

Simple Animal Model Enables Embrace of Cancer Complexity

By Anette Breindl
Science Editor

Monday, June 18, 2012
One of the disappointments of targeted cancer therapies has been that their promise of low toxicity has not been borne out. At the American Society of Clinical Oncology conference earlier this month, Geoffrey Shapiro of the Dana-Farber Cancer Institute told BioWorld Today that "alopecia" – hair loss – "and bone marrow toxicity have been replaced by diarrhea and rash" as the dose-limiting banes of therapeutic development.

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