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Taking Off the Brakes

Stem Cell Advance Transforms the 1% into the 99%

By Anette Breindl
Science Editor

Thursday, September 19, 2013
Researchers have identified a protein that is critical for keeping adult cells from turning back into induced pluripotent stem (iPS) cells. In cells that lack this protein, the transcription factor cocktail that is used to turn cells into iPS cells worked basically without fail; the efficiency of generating such cells skyrocketed from 1 percent of cells to more than 90 percent.

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