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Study reveals complex view of diabetes

By Anette Breindl
Science Editor

Tuesday, April 1, 2014
Researchers have identified a metabolite, the fatty acid CMPF, which is starkly elevated in the blood plasma of pregnant women with gestational diabetes and in both women and men with type 2 diabetes. CMPF could possibly be both a biomarker for and a therapeutic target against diabetes. But the study, which was published in the April 1, 2014, issue of Cell Metabolism, also showed that it was only one of many metabolites that differed in normal individuals and diabetics, leading senior author Michael Wheeler to assert that diabetes is “overly simplified as a disorder of blood sugar levels and insulin secretion.” “Our studies,” Wheeler told BioWorld Today, “would suggest that diabetes is a disease of nutritional imbalance.”

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