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T cells can go into training for enhanced cancer killing

By Sharon Kingman
Staff Writer

Friday, May 23, 2014
LONDON – It may be possible to develop a new type of immunotherapy that could efficiently eliminate all types of cancer cells, a new study suggests. The research, led by scientists at the University of Freiburg in Germany, found that stimulating a particular type of T cell with a monoclonal antibody turned the cells into highly effective killers. When the researchers added these stimulated T cells to cancer cells in the laboratory, all the cancer cells died within four hours. Wolfgang Schamel, professor of immunology at the University of Freiburg, told BioWorld Today, "With conventional protocols, not all the cells are killed in these types of experiments, and it takes longer. But we repeated these experiments many times and each time we obtained a huge effect."

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