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'Working on the Wiring'

Transcription Factor Mapping Yields New Tuberculosis Clues

By Anette Breindl
Science Editor

Monday, July 8, 2013
By taking an in-depth look at the transcription factor network of Mycobacterium tuberculosis, researchers have gained new insights into how the bacterium adapts to environmental changes, including conditions of low oxygen. For now, the team has looked at about a quarter of the more than 180 known transcription factors in the M. tuberculosis genome – 50 in all to date, though co-corresponding author Kyle Minch told BioWorld Today that "we are on our way to doing all of them."

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