U.S. Patent Disclosures

• Ariad Pharmaceuticals Inc., of Cambridge, Mass., received U.S. Patent No. 8,114,874, titled "Substituted Acetylenic Imidazo[1,2-B] Pyridazine Compounds as Kinase Inhibitors." It provides composition-of-matter protection for investigational pan-Bcr-Abl inhibitor ponatinib.