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IN THE CLINIC NEWS
After Friday's market close, while much of the U.S. had already turned its attention to the long Memorial Day weekend, Amgen Inc. quietly axed its stake in brodalumab, the much-heralded IL-17 inhibitor that was part of a co-development and commercialization deal with partner Astrazeneca plc.

Mast Therapeutics Inc. has initiated a new open-label extension study to evaluate repeat dosing of its experimental sickle cell disease (SCD) therapy, vepoloxamer (MST-188).

With primary endpoint-missing phase IIb data in hand, Otonomy Inc. CEO David Weber said he is "more confident today" that OTO-104 for Meniere's disease is a viable product, and the company will be meeting with the FDA to talk about the planned phase III program.

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