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Portola Pharmaceuticals Inc.'s shares (NASDAQ:PTLA) rose 6.4 percent Monday as the company advanced its global pivotal trial of betrixaban, testing how well the drug prevents blood clots when patients are hospitalized for critical cardiovascular conditions and following their release.

Alkermes plc said Tuesday that favorable phase III data on its long-acting injectable antipsychotic (LAI), aripiprazole lauroxil, will support its filing an FDA new drug application for the investigational schizophrenia treatment in the third quarter.

Oncothyreon Inc. said that Merck KGaA has started a phase III trial of its out-licensed cancer vaccine tecemotide in patients with unresectable, locally advanced stage III non-small-cell lung cancer (NSCLC).

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