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Pharma: clinic roundup

Astrazeneca plc , of London, (AZN) said patient enrollment was completed approximately four months ahead of plan in the phase III trial EUCLID studying Brilinta (ticagrelor) tablets. (BioWorld-Today-2014-03-18) ...

BioWorld Today - Staff - 2014-03-18 00:00 - 0 comments - 0 attachments

Clinic roundup

Achillion Pharmaceuticals Inc. , of New Haven, Conn., said presentations at the Asian Pacific Association for the Study of the Liver in Brisbane, Australia, included updated phase II results evaluating a 150-mg loading dose following by 50 mg once da ...

BioWorld Today - Staff - 2014-03-17 00:00 - 0 comments - 0 attachments

Clinic roundup

Idera Pharmaceuticals Inc. , of Cambridge, Mass., said it plans to start clinical development of its lead compound, IMO-8400, for the treatment of patients with polymyositis and patients with dermatomysitis, two orphan autoimmune diseases. ...

BioWorld Today - Staff - 2014-03-14 00:00 - 0 comments - 0 attachments

Pharma: clinic roundup

Glaxosmithkline plc (GSK), of London, said a pivotal phase III study of mepolizumab, an investigational IL-5 antagonist monoclonal antibody, met its primary endpoint of reducing the frequency of exacerbations in patients with severe eosinophilic ast ...

BioWorld Today - Staff - 2014-03-14 00:00 - 0 comments - 0 attachments

Clinic roundup

Senesco Technologies Inc. , of Bridgewater, N.J., opened two sites in the Republic of South Africa in its open-label, multiple-dose, dose-escalation phase Ib/IIa study of SNS01-T, which is evaluating the safety and tolerability in 15 patients wit ...

BioWorld Today - Staff - 2014-03-13 00:00 - 0 comments - 0 attachments

Pharma: clinic roundup

Pfizer Inc. , of New York, reported that detailed results of the Community-Acquired Pneumonia Immunization Trial in Adults, or CAPiTA, which enrolled approximately 85,000 subjects, demonstrated that Prevenar 13 (pneumococcal polysaccharide conjugat ...

BioWorld Today - Staff - 2014-03-13 00:00 - 0 comments - 0 attachments

Clinic roundup

Cytonet GmbH & Co. KG , of Weinheim, Germany, said interim data on its liver cell therapy treatment presented at the Society for Inherited Metabolic Disorders meeting in Pacific Grove, Calif., showed that pediatric patients with urea cycle disord ...

BioWorld Today - Staff - 2014-03-12 00:00 - 0 comments - 0 attachments

Clinic roundup

Betagenon AB and Baltic Bio AB , both of Stockholm, said phase I studies began with O304, an orally available AMPK activator. (BioWorld-Today-2014-03-11) ...

BioWorld Today - Staff - 2014-03-11 00:00 - 0 comments - 0 attachments

Clinic roundup

Northwest Biotherapeutics Inc. , of Bethesda, Md., said the data safety monitoring board has made an unblinded review of the safety data for the company’s ongoing international phase III glioblastoma trial with DCVax-L, using activated dendritic ce ...

BioWorld Today - Staff - 2014-03-10 00:00 - 0 comments - 0 attachments

Clinic Roundup

Biogen Idec Inc. , of Weston, Mass., and Swedish Orphan Biovitrum AB , of Stockholm, Sweden, disclosed positive results from A-LONG, a Phase III trial that evaluated a long-lasting clotting factor candidate in people with hemophilia A. (B ...

BioWorld Today - Staff - 2013-12-06 01:00 - 0 comments - 0 attachments