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Pharma: Clinic Roundup

• LEO Pharma UK , of Princes Risborough, UK, reported that data published in the Journal of the American Medical Association Dermatology demonstrated the long-term effectiveness of Picato (ingenol mebutate) in treating actinic keratosis (AK ...

BioWorld Today - Staff - 2013-03-22 00:00 - 0 comments - 0 attachments

Pharma: Clinic Roundup

Merck & Co. Inc., of Whitehouse Station, N.J., is collaborating with Glaxosmithkline plc, of London, to test Merck’s anti-PD-1 immunotherapy, MK-3475, with GSK’s oral kinase inhibitor, pazopanib, in advanced renal cell carcinoma. The compani ...

BioWorld Today - Staff - 2013-12-19 01:00 - 0 comments - 0 attachments

Pharma: Clinic roundup

Ipsen SA , of Paris, reported initial results from the 243-patient Phase III study of Dysport (abobotulinumtoxinA) in adult upper limb spasticity, showing statistically significant response vs. placebo in the improvement of muscle tone, as measured ...

BioWorld Today - Staff - 2013-12-18 01:00 - 0 comments - 0 attachments

Pharma: Clinic roundup

Boehringer Ingelheim GmbH , of Ingelheim, Germany, reported new data from its Phase III trial, Startverso, which evaluated faldaprevir in combination with pegylated interferon and ribavirin (PegIFN/RBV) in patients with genotype-1 hepatitis C (HCV) ...

BioWorld Today - Staff - 2013-12-17 01:00 - 0 comments - 0 attachments

Pharma: Clinic roundup

Takeda Pharmaceutical Co. Ltd., of Osaka, Japan, reported results showing that pantoprazole magnesium 40 mg, branded Tecta, was as effective as esomeprazole 40 mg for achieving complete remission in patients with erosive gastroesophageal reflux disease, ...

BioWorld Today - Staff - 2013-12-16 01:00 - 0 comments - 0 attachments

Pharma: clinic roundup

Mallinckrodt Inc. , of St. Louis, said the Phase III trial of MNK-155, an extended-release oral formulation of hydrocodone and acetaminophen, met the primary efficacy endpoint of change in pain from baseline over 48 hours compared to placebo in manag ...

BioWorld Today - Staff - 2013-12-13 01:00 - 0 comments - 0 attachments

Pharma: Clinic roundup

Merck & Co. Inc. , of Whitehouse Station, N.J., said the data monitoring committee for the Phase II/III EPOCH study testing MK-8931, an oral beta-amyloid precursor protein site-cleaving enzyme, or BACE, inhibitor, in mild to moderate Alzheimer’s ...

BioWorld Today - Staff - 2013-12-11 01:00 - 0 comments - 0 attachments

Pharma: Clinic roundup

Summit Corp. plc, of Oxford, UK, said the first Duchenne Muscular Dystrophy (DMD) patient has been enrolled and dosed in a Phase Ib clinical trial of the oral, small molecule utrophin modulator SMT C1100. (BioWorld-Today-2013-12-10) ...

BioWorld Today - Staff - 2013-12-10 01:00 - 0 comments - 0 attachments

Pharma: Clinic roundup

Shire plc , of London, reported top-line Phase III results with its lifitegrast dry-eye treatment. (BioWorld-Today-2013-12-09) ...

BioWorld Today - Staff - 2013-12-09 01:00 - 0 comments - 0 attachments

Pharma: Clinic roundup

Eli Lilly and Co., of Indianapolis, reported that three Phase III studies of edivoxetine failed to meet the primary objective of superior efficacy in major depressive disorder (MDD) after eight weeks of treatment. When added to a selective serotonin ...

BioWorld Today - Staff - 2013-12-06 01:00 - 0 comments - 0 attachments