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CAR-T cell therapy

A new report published by Boston's Institute for Clinical and Economic Review concludes that two pricey new CAR-T cell therapies, Novartis AG's Kymriah and Gilead Sciences Inc.'s Yescarta, both provided moderate certainty of a small to substantial net health benefit.

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GWAS in Chinese population implicates immune system in Alzheimer's disease

A study has identified common genetic variants in the Chinese population contributing to the risk of developing Alzheimer's disease (AD) that possibly exert functional effects through the immune system, which could have important implications for AD management.

The search continues for promising biomarkers and effective disease-modifying therapies for AD. The current drug development approaches mainly target the disease's hallmark pathology of amyloid-beta (Abeta) protein accumulation in the brain leading to Abeta plaque deposition.



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