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Region of opportunity aMENAble to drug development

MENA – the Middle East and North Africa. As a region, it's got everything a drugmaker could want. An expanding and aging population. Unmet medical need. A growing middle class. The desire and the ability to pay for branded and generic therapies. more »

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Nanoparticle quells inflammation in sepsis and ARDS

Researchers at Queens University Belfast have developed a nanoparticle that could dampen inflammatory responses and improve survival in animal models of both sepsis and acute respiratory distress syndrome, both major causes of death and disability in hospitalized patients.

The particles consist of a specific type of sialic acid coated onto poly(lactic-co-glycolic acid) (PLGA) nanoparticles that target siglec-E, a surface receptor that is important for dampening the inflammatory responses of macrophages.



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