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Oral now, I.V. version in a year
The staying power of FDA-approved oral Varubi (rolapitant) for chemotherapy-induced nausea and vomiting (CINV) should provide an edge in the marketplace, Tesaro Inc. more »

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Nanoparticle quells inflammation in sepsis and ARDS

Researchers at Queens University Belfast have developed a nanoparticle that could dampen inflammatory responses and improve survival in animal models of both sepsis and acute respiratory distress syndrome, both major causes of death and disability in hospitalized patients.

The particles consist of a specific type of sialic acid coated onto poly(lactic-co-glycolic acid) (PLGA) nanoparticles that target siglec-E, a surface receptor that is important for dampening the inflammatory responses of macrophages.



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