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Flagship Ventures' latest $537 million raise for its fifth fund – the largest since the firm's founding in 2000 – will let its Venturelabs innovator unit, which has been churning out two new companies per year, generate four to five in the future. more »

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Breaking mirror images for patients' good luck

Given the precision of chemical synthesis processes, small-molecule drugs can be a surprisingly mixed bag of molecules.

If a molecule has a chiral center, synthesis will give a mixture of two molecules that have the identical chemical composition but are mirror images of each other. Technically speaking, they are enantiomers. In the macrobiological world, a person's left and right hand are enantiomers of each other.

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