LONDON – A new frontier has opened up in the search for Alzheimer's therapies, with researchers at Massachusetts Institute of Technology reporting they can reduce beta amyloid plaques in mouse models using lights flickering at specific frequencies to stimulate neural circuits.
SAN DIEGO Fixing genetic diseases such as hemophilia, sickle-cell disease, and certain immunodeficiencies at their root, by replacing or repairing the faulty gene, has gone from dream to drug, with two gene therapies now approved in Europe, and a number of additional approvals expected on both sides of the Atlantic over the next few years.more »
- FDA clears IND for first China-made biologic: Alphamab's KN035
- On a scale of 1-10: Earth gets a 3 for infectious disease readiness
- Indian court overrules controversial ban on 344 fixed-dose combos
- Opdivo price cut 50% in Japan after controversial emergency review
- First steps taken toward neutralizing Zika virus
With just one month to go before biopharma draws the curtains on a year that has seen its fair share of lows for the sector, it received an early Christmas present following Donald Trump's unexpected victory in the presidential election. Share values of drug developers have soared in the wake of the result because it came with the removal, at least for now, of fears that drug-pricing policy issues will be high on the political agenda going forward.
"Basically, it's not easy to define what will serve humanity."
So said Yoshinori Ohsumi, honorary professor at the Tokyo Institute of Technology, after winning the 2012 Kyoto Prize in Life Sciences for his research.
The Nobel Assembly followed suit in recognizing the importance of Ohsumi's work, awarding him the 2016 Nobel Prize in Physiology or Medicine to "for his discoveries of mechanisms for autophagy."READ MORE »
- First steps taken toward neutralizing Zika virus »
- Medicine's future is precise, if still uncertain »
- Quorum sensing controls adaptive immunity via CRISPR »
- Tau phosphorylation inhibits plaque toxicity in AD mice »
- Drug shows promise in preventing pre-term birth in mice »
- Cachexia is linked to immunotherapy failure »
- Circuit-specific receptor targeting fights epilepsy »
- Bacterial metabolite shows activity in breast cancer »
- Stimulating, blocking rapid-acting estrogen receptor both beneficial »
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