Researchers at Boston Children's Hospital have used a novel type of screening to identify a compound that caused massive weight loss in mice with diet-induced obesity, causing them to lose 45 percent of their body weight. more »
In a self-declared "love fest," the House Energy and Commerce Committee put aside partisan politics Thursday, voting 51-0 to pass the 21st Century Cures Act, H.R. 6, in the hope of streamlining the process of developing and approving new medical treatments. more »
Defending patents for drugs and medical devices is part of the stakes of an R&D budget, but the size of that stake could increase significantly if a hedge fund manager wins his inter partes review (IPR) challenge of selected drug patents. more »
- Regeneron, Sanofi score phase III sarilumab win; adds anti-TNF resisters
- Skin in the game: Argen-x, Leo in $116M MAb dermatology pact
- Bill 'Cures' partisanship in House committee love fest with 51-0 vote
- Cures bill allocates $550M for FDA; agency indicates it may need $958M
- China's drug price cap removal likely to benefit...
- Pharmaxis gets $31M up front as Boehringer Ingelheim joins the dash for NASH
- Bharat Biotech battles the high cost of vaccines, one disease at a time
- Orexigen Therapeutics in public crosshairs on CVOT data, Takeda Pharmaceutical dispute
- Beigene’s $97M financing lands as it prepares for global expansion
- Occurx launches down under to tackle ocular fibr...
Migraine is a complex neurological phenomenon manifesting in painful headaches that can be extremely debilitating which, according to the World Health Organization, ranks it in the top four disabling neurological conditions affecting almost 20 percent of the world's population.
A genomics-based search for better drug targets for painkillers has turned up a candidate that is, in one sense, not new at all.
That candidate is the nicotinic acetylcholine receptor, already the beneficiary of one failed round of drug development.
But the new study, which was published in the May 13, 2015, issue of Science Translational Medicine, suggests that targeting a different subunit of the receptor, and doing so in the periphery, may yield better clinical results.READ MORE »
- WGS helps those sequenced, and possibly others, get a diagnosis »
- Engineered phages can kill antibiotic resistance genes »
- CRISPR surgical strikes aid cancer target discovery »
- New blood pressure finding could lead to new treatments »
- GTEx data look at tissue differences in genome's effects »
- Astrocytes lock down neurons in RASopathies »
- Chinese-U.S. study provides clues to treating aging disorders »
- Novel brown fat regulation target identified in Singapore »
- Genomic, functional analyses point way to new glioma therapy »
- You’ve come a long way, baby, but still a long way to goMay 04, 2015 | 2:44 PM | Posted by: Mari Serebrov
- As researchers unlock the brain’s mysteries, let’s not overlook the real questionsApril 27, 2015 | 4:35 PM | Posted by: Marie Powers
- Talk to your doctor: How even annoying DTC ads can contribute to patient communication April 15, 2015 | 4:48 PM | Posted by: Jennifer Boggs
- Sharing deeply of ourselves: Still messyMarch 27, 2015 | 11:17 PM | Posted by: Michael Fitzhugh
- Patient engagement as important as the dataFebruary 20, 2015 | 5:50 PM | Posted by: Mari Serebrov
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