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Realizing the power of the genome

LONDON – Decode Genetics Inc. has raised the insight genomics brings to the understanding of human disease to a new level through the sequencing of the complete genomes of 2,636 Icelanders, an advance the Amgen Inc. subsidiary claims has deep implications for clinical translation and the rollout of precision medicine. more »

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Breaking mirror images for patients' good luck

Given the precision of chemical synthesis processes, small-molecule drugs can be a surprisingly mixed bag of molecules.

If a molecule has a chiral center, synthesis will give a mixture of two molecules that have the identical chemical composition but are mirror images of each other. Technically speaking, they are enantiomers. In the macrobiological world, a person's left and right hand are enantiomers of each other.



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