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Other dogs bark up CGRP tree

The contest to find a better migraine drug in the calcitonin gene-related peptide pathway had fallout for Alder Biopharmaceuticals Inc. as the company unveiled what were called "strongly positive" phase III Promise 1 data – despite a hefty placebo response – with eptinezumab, its lead product candidate to prevent such headaches.

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Clearing senescent cells, restoring progenitor stem cells to reverse age-related disease

SAN DIEGO – Nobody wants to get old. Health declines, disease increases and insurance costs skyrocket. But what if researchers could slow the process at the cellular level, reverting stem cells to their youthful state, or clearing senescent cells, a hallmark of advanced years?

Two companies working in the space presented their research at the BIO convention during a session titled "Reimagine Old Age: New Frontiers in the Science of Aging."

The aging process involves a loss of homeostasis, with messy DNA and reduced gene expression.READ MORE »

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