The Medicines and Healthcare Products Regulatory Agency of the UK approved a 300-patient Phase III trial of Northwest Biotherapeutics Inc.'s DCVax-L for glioblastoma multiforme (GBM). Phase III is in full swing in the U.S., at 41 clinical sites, but Northwest seeks to expand the trial to international sites, starting in the UK, stating it will save several years' time by not carrying out separate U.S. and European trials.